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日期:2024-08-29
APC基因是種腫瘤抑制基因(tumor suppressor gene),當APC基因發生突變時,它所
轉譯的蛋白產物將失去功能,而造成細胞病變,這與結腸癌的罹患率及預後有密切 ......
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日期:2024-08-28
Eur J Cancer. 2002 May;38(7):867-71. The APC gene in colorectal cancer.
Fodde R(1). Author information: (1)Department of Human and Clinical Genetics, ......
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日期:2024-08-30
How are changes in the APC gene related to health conditions? desmoid tumor -
caused by mutations in the APC gene. Several ......
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日期:2024-09-01
Complete information for APC gene (protein-coding), adenomatous polyposis
coli, including: function, proteins, disorders, pathways, orthologs, and expression....
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日期:2024-08-31
The APC gene encodes a multidomain protein that plays a major role in tumor
suppression by antagonizing the WNT (see WNT1; 164820) signaling pathway....
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日期:2024-08-29
1 Oct 2007 ... Summary. The adenomatous polyposis coli (APC) gene is a key tumor
suppressor gene. Mutations in the gene have been found not only in ......
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日期:2024-08-30
Mutations in the adenomatous polyposis coli (APC) gene are not only
responsible for familial adenomatous polyposis (FAP), but also play a rate-
limiting role in....
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日期:2024-08-31
21 Dec 2014 ... The APC gene product indirectly regulates transcription of a number of critical
cell proliferation genes, through its interaction with the ......