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日期:2024-07-08
Ionizing radiation (IR) is used for patients diagnosed with unresectable non small cell lung cancer (NSCLC), however radiotherapy remains largely palliative due to radioresistance. Cancer stem cells (CSCs), as well as epithelial-mesenchymal transition (EM...
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日期:2024-07-05
Review Series Cancer stem cells in the development of liver cancer Taro Yamashita 1 and Xin Wei Wang 2 1 Department of General Medicine, Kanazawa University Hospital, Kanazawa, Ishikawa, Japan. 2 Laboratory of Human Carcinogenesis, Center for Cancer ......
CD44v6 Is a Marker of Constitutive and Reprogrammed Cancer Stem Cells Driving Colon Cancer Metastasi
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日期:2024-07-10
Cancer stem cells drive tumor formation and metastasis, but how they acquire metastatic traits is not well understood. Here, we show that all colorectal cancer ... Figure 1. Metastatic CRC Cells Express CD44v6 (A) Percentage of CD44v6 and CD133 on gated ....
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日期:2024-07-10
The cancer stem cell (CSC) theory is gaining increasing attention from researchers and has become an important focus of cancer research. According to the theory ... 1. Introduction Solid tumors similar to aberrantly developed organs and tissues are compos...
Cancer Stem Cells in Solid Tumours: Evidence and Unresolved Questions: Non-adherent Sphere Assays fo
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日期:2024-07-04
Ex vivo and in vivo assays for tumour cells. a | The non-adherent sphere assay predicts that a cancer stem cell (CSC) can be serially passaged for many cycles and that it generates a tumour sphere resembling the primary sphere in each case. b | Tumour cel...
International Journal of Oral Science - Sphere-forming-like cells (squamospheres) with cancer stem-l
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日期:2024-07-06
Original Article International Journal of Oral Science (2014) 6, 212–218; doi:10.1038/ijos.2014.32; published 11 July 2014 Sphere-forming-like cells (squamospheres) with cancer stem-like cell traits from VX2 rabbit buccal squamous cell carcinoma Yuk-Kwan ...
Oncogene - VEGF drives cancer-initiating stem cells through VEGFR-2/Stat3 signaling to upregulate My
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日期:2024-07-06
Oncogene is one of the world’s leading cancer journals. It is published weekly and covers all aspects of the structure and function of Oncogenes. ... Top of page Results VEGF stimulates ALDH1 activity and serial mammosphere formation Sphere assays reflect...
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日期:2024-07-05
Methods We illustrate the key roles that cancer stem cells and the tumor microenvironment—particularly the lymph node stromal microenvironment—play in tumor drug resistance, metastasis, and recurrence in 2 representative cancers: colorectal cancer and ......