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日期:2024-12-19
The MAPK/ERK pathway (also known as the Ras-Raf-MEK-ERK pathway) is a chain of proteins in the cell that communicates a signal from a receptor on the surface of the cell to the DNA in the nucleus of the cell. The signal starts when a signaling molecule bi...
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日期:2024-12-23
Expert-reviewed pathway providing a current overview of p38 MAPK Signaling, a pathway description, select PubMed references, and links to PhosphoSitePlus. ... Pathway Description: p38 MAPKs (α, β, γ, and δ) are members of the MAPK family that are activate...
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日期:2024-12-25
Skeletal muscle aging results in a gradual loss of skeletal muscle mass, skeletal muscle function and regenerative capacity, which can lead to sarcopenia and increased mortality. Although the mechanisms underlying sarcopenia remain unclear, the skeletal m...
CST - p44/42 MAPK (Erk1/2) Antibody - Cell Signaling Technology (CST): Antibodies, Reagents, Proteom
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日期:2024-12-19
Polyclonal Antibody for studying ERK1/ERK2 in the MAPK Signaling research area. ... Western blot analysis of extracts from HeLa cells transfected with 100 nM control siRNA #6201 (-) or p44 MAPK (Erk1) siRNA (+), using p44/42 MAPK (Erk1/2) Antibody #9102 ....
Colon cancer cells colonize the lung from established liver metastases through p38 MAPK signalling a
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日期:2024-12-20
1. Nat Cell Biol. 2014 Jul;16(7):685-94. doi: 10.1038/ncb2977. Epub 2014 Jun 1. Colon cancer cells colonize the lung from established liver metastases through p38 MAPK signalling and PTHLH. Urosevic J, Garcia-Albéniz X, Planet E, Real S, Céspedes MV, Guiu...
Colon cancer cells colonize the lung from established liver metastases through p38 MAPK signalling a
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日期:2024-12-24
Gomis and colleagues report on the mechanisms driving colon cancer metastasis. They show that whereas ERK2 activity promotes colon cancer metastasis to the liver, reduced p38 signalling upregulates the PTHLH cytokine to allow liver metastatic cell ......
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日期:2024-12-23
Signaling pathways that activate different mitogen-activated protein kinases (MAPKs) elicit many of the responses that are evoked in cells by changes in certain environmental conditions and upon exposure to a variety of hormonal and other stimuli. These p...
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日期:2024-12-21
Genentech BioOncology is currently conducting research on how MAP kinase signaling pathway plays a vital role in cell proliferation and differentiation. Learn how MAPK signaling is initiated and transmitted through a series of molecular events....