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日期:2024-07-08
The hematopoietic stem cell (HSC) niche is the anatomical location in which HSCs reside and self-renew. The HSCs outside the niche do not self-renew and commence the process of differentiation to ultimately produce mature blood cells. In recent years ther...
JCI - Human prostate cancer metastases target the hematopoietic stem cell niche to establish foothol
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日期:2024-07-11
Research Article Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow Yusuke Shiozawa 1, Elisabeth A. Pedersen 1, Aaron M. Havens 1, 2, Younghun Jung 1, Anjali Mishra 1, Jeena Joseph 1, Jin ...
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日期:2024-07-09
Stem cell niche refers to a microenvironment where stem cells are found, which
interacts with stem cells to regulate cell fate. The word 'niche' can be in ......
JCI - Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem c
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日期:2024-07-06
Technical Advance Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells Jennifer L. Gori 1, Jason M. Butler 2, 3, Yan-Yi Chan 1, Devikha Chandrasekaran 1, Michael G. Poulos 2, 3, Michael Ginsberg 4, Daniel J .....
Hematopoietic stem cell niche maintenance during homeostasis and regeneration : Nature Medicine : Na
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日期:2024-07-11
The maintenance and proliferation of hematopoietic stem cells after injury is regulated by signals from the bone marrow stem cell niche. ... Quiescent HSCs localize to small arterioles of the endosteal region, which are ensheathed by NG2 + nestin bright p...
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日期:2024-07-04
Hematopoietic Stem Cell Arrival Triggers Dynamic Remodeling of the Perivascular Niche Owen J. Tamplin 1, 6, Ellen M. Durand 1, 2, 6, Logan A. Carr 1, Sarah J. Childs 3, Elliott J. Hagedorn 1, Pulin Li 1, 4, 7, Amanda D. Yzaguirre 5, Nancy A. Speck 5, Leon...
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日期:2024-07-04
1. Cell Stem Cell. 2011 Oct 4;9(4):298-310. doi: 10.1016/j.stem.2011.09.010. Metabolic regulation of hematopoietic stem cells in the hypoxic niche. Suda T(1), Takubo K, Semenza GL. Author information: (1)Department of Cell Differentiation, The ......
3D co-culture of hematopoietic stem and progenitor cells and mesenchymal stem cells in collagen scaf
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日期:2024-07-04
3D co-culture of hematopoietic stem and progenitor cells and mesenchymal stem cells in collagen scaffolds as a model of the hematopoietic niche Isabelle Leisten a, Rafael Kramann a, b, 1, Mónica S. Ventura Ferreira a, c, Manfred Bovi a, d, Sabine Neuss a,...