search:induced pluripotent stem cells in cardiovascular d相關網頁資料

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日期:2024-07-08
Induced stem cells (iSC) are stem cells artificially derived from somatic, reproductive, pluripotent or other cell types by deliberate epigenetic reprogramming. They are classified as either totipotent (iTC), pluripotent (iPSC) or progenitor (multipotent—...
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日期:2024-07-02
As mentioned previously, hypertrophic cardiomyopathy is one of the major features of LS, affecting 80% of the patients. In addition, affected individuals occasionally manifest hematologic complications such as myelodysplasia and leukemia 16, 17. Therefore...
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Characterization of Pluripotent Stem Cell Clones The characteristics of each established iPS cell line can be evaluated by several methods. 35 Reverse-transcription polymerase chain reaction and immunocytochemistry can be used to evaluate specific genes o...
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日期:2024-07-03
1. Nat Med. 2014 Jun;20(6):616-23. doi: 10.1038/nm.3545. Epub 2014 May 11. Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies. Wang G(1), McCain ML(2), Yang L(3), He A(4 ......
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Original Article Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome Alessandra Moretti, Ph.D., Milena Bellin, Ph.D., Andrea Welling, Ph.D., Christian Billy Jung, M.Sc., Jason T. Lam, Ph.D., Lorenz Bott-Flügel, M.D., Tatjana Dorn, P...
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The human induced pluripotent stem cells (hiPSCs) are derived from a direct reprogramming of human somatic cells to a pluripotent stage through ectopic expression of specific transcription factors. These cells have two important properties, which are the ...
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日期:2024-07-05
Worldwide increases in life expectancy have been paralleled by a greater prevalence of chronic and age-associated disorders, particularly of the cardiovascular, neural and metabolic systems. This has not been met by commensurate development of new drugs a...
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日期:2024-07-08
Embryonic stem (ES) cells are pluripotent stem cells derived from the inner cell mass of preimplantation embryos. Induced pluripotent stem (iPS) cells can be generated by somatic cell reprogramming following the exogenous expression of specific transcript...