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      • en.wikipedia.org
        Cancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a...
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      • www.jci.org
        Review Series Cancer stem cells in the development of liver cancer Taro Yamashita 1 and Xin Wei Wang 2 1 Department of General Medicine, Kanazawa University Hospital, Kanazawa, Ishikawa, Japan. 2 Laboratory of Human Carcinogenesis, Center for Cancer ...
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    日期:2024-07-09
    TNFα sensitizes neuroblastoma cells to FasL-, cisplatin- and etoposide-induced cell death by NF-κB-mediated expression of Fas Galenkamp KMO, Carriba P, Urresti J, Planells-Ferrer L, Coccia E, Lopez-Soriano J, Barneda-Zahonero B, Moubarak RS et al. Molecul...
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    日期:2024-07-08
    The cancer stem cell (CSC) theory is gaining increasing attention from researchers and has become an important focus of cancer research. According to the theory ... 1. Introduction Solid tumors similar to aberrantly developed organs and tissues are compos...
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    日期:2024-07-08
    Methods We illustrate the key roles that cancer stem cells and the tumor microenvironment—particularly the lymph node stromal microenvironment—play in tumor drug resistance, metastasis, and recurrence in 2 representative cancers: colorectal cancer and ......
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    日期:2024-07-14
    Cell death and differentiation is a monthly research journal focused on the exciting field of programmed cell death and apoptosis. It provides a single accessible source of information for both scientists and clinicians, keeping them up-to-date with advan...
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    日期:2024-07-15
    During development and through life, stem cells may be exposed to a variety of physical signals, including tensile, compressive, shear, osmotic, and fluid stresses, often arising secondarily to biomechanical interactions with their ECM. For example, tensi...
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    日期:2024-07-15
    Protein networks that establish the apical and basolateral domains. Epithelial cells orient their basal surface through the adhesion of integrin receptors to the extracellular matrix, and they extend membrane protrusions, known as filopodia, to contact ne...
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    日期:2024-07-13
    Pain in cancer may arise from a tumor compressing or infiltrating nearby body parts; from treatments and diagnostic procedures; or from skin, nerve and other changes caused by a hormone imbalance or immune response. Most chronic (long-lasting) pain is cau...
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    日期:2024-07-11
    1. Introduction Aldehyde dehydrogenases (ALDH) belong to the oxidoreductase family, which catalyze the conversion of aldehydes to their corresponding acids. As a group of NAD(P)+-dependent enzymes, aldehyde dehydrogenases (ALDHs) are involved in oxidation...