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JCI - Autologous mesenchymal stem cell–derived dopaminergic neurons function in parkinsonian macaque
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日期:2024-08-08
Evaluation of MSC-DP cells. Cynomolgus monkey MSCs drastically changed their morphology following induction, as reported previously (21): naive MSCs initially showed fibroblast-like mesenchymal cell features (Figure 1A), while induced cells showed a neuro...
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日期:2024-08-03
1. Introduction Obesity and diabetes are the major health challenges for the twenty first century, according to a recent report by the International Diabetes Foundation. The connection between obesity and diabetes is evident in sharing the same risk facto...
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日期:2024-08-03
Top of page Abstract Mesenchymal stem cells (MSCs) are partially defined by their ability to differentiate into tissues including bone, cartilage and adipose in vitro, but it is their trophic, paracrine and immunomodulatory functions that may have the gre...
Immunomodulatory characteristics of mesenchymal stem cells and their role in the treatment of Multip
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日期:2024-08-05
The main claim Number of patients Refs. Intrathecal Infusion of ex vivo expanded MSCs was associated with some ameliorative effects 10 [140] The intravenously and intrathecally injected mesenchymal-like stem cells attenuate disease symptoms 4 [141] The .....
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日期:2024-08-07
Top of page Properties of Mesenchymal Stem Cells MSCs exist in almost all tissues, and have the capacity of self-renewal and the potential to differentiate into multiple cell types. Under certain physiological and experimental conditions, MSCs differentia...
Stem Cell Research & Therapy | Full text | Mesenchymal stem cells inhibit multiple myeloma cells via
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日期:2024-08-02
Figure 1. Effect of mesenchymal stem cell infusion in multiple myeloma model mice. (A) Experimental protocol of multiple myeloma (MM) cell and mesenchymal stem cell (MSC) injection and the design of lymphocyte Peyer’s patch adhesion molecule (LPAM ......
Stem Cell Research & Therapy | Full text | Mesenchymal stem cell-derived exosomes promote hepatic re
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日期:2024-08-02
Exosomes reduced liver-injury level in ALT and AST after CCl 4 treatment in vivo A preliminary experiment revealed that serum AST and ALT gradually increased and peaked at 24 hours after a single dose of CCl 4 (data not shown). Thus, AST and ALT were ......
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日期:2024-08-06
To assess the safety and feasibility of allogeneic human umbilical cord blood (hUCB)-derived mesenchymal stem cell (MSC) transplantation in preterm infants.In a ... Inclusion criteria included preterm infants at high-risk for developing BPD 15 with a gest...