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Organ reengineering through development of a transplantable recellularized liver graft using decellu
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日期:2024-12-16
A critical donor organ shortage currently limits the treatment of patients with severe liver failure. Building on earlier work with decellularized hearts, Basak Uygun et al. have developed a transplantable liver graft using a decellularized liver matrix. ...
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日期:2024-12-15
The extracellular matrix (ECM) of mammalian tissues has been isolated, decellularized and utilized as a scaffold to facilitate the repair and reconstruction of ... 2.2. Demineralization and decellularization Cancellous bone granules were demineralized usi...
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日期:2024-12-19
Methods A combination of enzymatic, detergent, and mechanical methods are used to remove all cells from isolated rat livers. Whole-organ perfusion is used in a customized organ chamber and the decellularized livers are examined by morphologic, biochemical...
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日期:2024-12-22
Fig. 2. Example of a decellularized lung slice from a mouse subjected to intratracheal infusion of bleomycin to induce lung fibrosis. Accumulation of collagen (immunostained in red) and loss of normal lung structure appearance was distributed in a clearly...
Cutting-Edge Regenerative Medicine Technologies for the Treatment of Heart Valve Calcification | InT
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日期:2024-12-19
2.1.2. Decellularized extracellular matrices Despite the evident ability of these biopolymers to undergo cell remodelling, a proper mature, cell-operated tissue architectural reconstitution might require a chemo-mechanical stimulation for a long time. Oft...
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日期:2024-12-20
The Future Is Here: Regenerative Powder, Ink Jet Heart Cells And Custom-Made Body Parts ... Imagine re-growing a severed fingertip, or creating an organ in the lab that can be transplanted into a patient without risk of rejection....
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日期:2024-12-19
It is commonly stated that tissue engineering is the most promising approach to treat or replace failing tissues/organs. For this aim, a specific strategy should be planned including proper selection of biomaterials, fabrication techniques, cell lines, an...
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日期:2024-12-15
We are now well entering the exciting era of stem cells. Potential stem cell therapy holds great promise for the treatment of many diseases such as stroke, traumatic brain injury, Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral-sclerosis, my...