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日期:2024-07-11
Stem cell niche refers to a microenvironment where stem cells are found, which interacts with stem cells to regulate cell fate. The word 'niche' can be in ......
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日期:2024-07-12
Studies on stem cells from diverse systems have shown that stem cell function is controlled by extracellular cues from the niche and by intrinsic genetic programs ......
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日期:2024-07-11
years it has become possible to identify stem cells and niches with increasing precision. ... in delineating stem cells and their niches, as well as in discover-....
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日期:2024-07-12
Stem cell niche refers to a microenvironment where stem cells are found, which interacts with stem cells to regulate cell fate. The word 'niche' can be in reference to the in vivo or in vitro stem cell microenvironment. During embryonic development, vario...
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日期:2024-07-08
Abstract Scientists have tried for decades to understand cancer development in the context of therapeutic strategies. The realization that cancers may rely on “cancer stem cells” that share the self-renewal feature of normal stem cells has changed the ......
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日期:2024-07-06
The hematopoietic stem cell (HSC) niche is the anatomical location in which HSCs reside and self-renew. The HSCs outside the niche do not self-renew and commence the process of differentiation to ultimately produce mature blood cells. In recent years ther...
JCI - Human prostate cancer metastases target the hematopoietic stem cell niche to establish foothol
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日期:2024-07-10
Research Article Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow Yusuke Shiozawa 1, Elisabeth A. Pedersen 1, Aaron M. Havens 1, 2, Younghun Jung 1, Anjali Mishra 1, Jeena Joseph 1, Jin ...
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日期:2024-07-12
A family business: stem cell progeny join the niche to regulate homeostasis Ya-Chieh Hsu & Elaine Fuchs doi:10.1038/nrm3272 Nature Reviews Molecular Cell Biology 13, 103 (2012) Stem cells reside in discrete microenvironments called niches, which regulate ...