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日期:2024-07-22
The actions of vasopressin are mediated by stimulation of tissue-specific G
protein-coupled receptors (GPCRs) called vasopressin receptors that are
classified ......
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日期:2024-07-17
Kidney Int Suppl. 1996 Jun;55:S177-82. Functional characterization of
vasopressin V1 and V2 receptors in the rabbit renal cortical collecting duct.
Yoshitomi K ......
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日期:2024-07-17
1. N Engl J Med. 2006 Nov 16;355(20):2099-112. Epub 2006 Nov 14. Tolvaptan, a selective oral vasopressin V2-receptor antagonist, for hyponatremia. Schrier RW, Gross P, Gheorghiade M, Berl T, Verbalis JG, Czerwiec FS, Orlandi C; SALT Investigators. ......
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日期:2024-07-18
The actions of vasopressin are mediated by stimulation of tissue-specific G protein-coupled receptors (GPCRs) called vasopressin receptors that are classified into V1, V2 and V3 subtypes.[1] These three subtypes differ in localization, function and signal...
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日期:2024-07-17
Original Article from The New England Journal of Medicine — Tolvaptan, a Selective Oral Vasopressin V2-Receptor Antagonist, for Hyponatremia ... Results Serum sodium concentrations increased more in the tolvaptan group than in the placebo group during the...
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日期:2024-07-23
1. Prog Brain Res. 2002;139:197-210. Nonpeptide vasopressin receptor antagonists: development of selective and orally active V1a, V2 and V1b receptor ligands. Serradeil-Le Gal C, Wagnon J, Valette G, Garcia G, Pascal M, Maffrand JP, Le Fur G. The involvem...
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日期:2024-07-20
A vasopressin receptor antagonist (VRA) is an agent which interferes with action at the vasopressin receptors. Most commonly VRAs are used in the treatment of hyponatremia, especially in patients with congestive heart failure, liver cirrhosis or SIADH.[1]...
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日期:2024-07-22
References: Hiroyama M, Wang S, Aoyagi T, Oikawa R, Sanbe A, Takeo S, Tanoue A: Vasopressin promotes cardiomyocyte hypertrophy via the vasopressin V1A receptor in neonatal mice. Eur J Pharmacol. 2007 Mar 22;559(2-3):89-97. Epub 2006 Dec 29. Pubmed ......