BMC Cancer | Full text | High resolution melting analysis of KRAS, BRAF and PIK3CA in KRAS exon 2 wi

BMC Cancer | Full text | High resolution melting analysis of KRAS, BRAF and PIK3CA in KRAS exon 2 wi

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日期:2024-08-22
KRAS is an EGFR effector in the RAS/RAF/ERK cascade that is mutated in about 40% of metastatic colorectal cancer (mCRC). Activating mutations in codons 12 and 13 of the KRAS gene are the only established negative predictors of response to anti-EGFR ......看更多