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Blood Journal | Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pres
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日期:2024-11-09
Ibrutinib is an irreversible inhibitor of ITK As a Th2-critical TEC family kinase, ITK retains significant structural and functional homology to ibrutinib’s known irreversible target BTK, including a Cys442 putative covalent binding moiety located within ...看更多