Crystal structure of the [micro]-opioid receptor bound to a morphinan antagonist : Nature : Nature P

Crystal structure of the [micro]-opioid receptor bound to a morphinan antagonist : Nature : Nature P

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日期:2024-10-31
a, b, The binding pocket of the μ-OR (a) is wide and open above the ligand, in stark contrast to the deeply buried binding pocket of the muscarinic receptors, as exemplified by the M3 receptor (b). c, Top, the small-molecule antagonist IT1t (magenta) occu...看更多